Vision Science Program UC Berkeley

Lab Research Activities

Nonlinear Systems Analysis with Application to Localizing VEP Sources A 3d rendered view of a brain.
Recent advances in functional imaging of brain activity using PET and fMRI has created much excitement among neuroscientists. Researchers are now able to extend their study of brain processing to humans. Unfortunately the new methodologies do not have adequate temporal resolution. Our recent research has produced a breakthrough in applying nonlinear analysis to the visual evoked potential (VEP) and magnetoencephalogram (MEG) enabling the underlying neural generators to be isolated with temporal resolution 1000 times better than is possible with either fMRI or PET and with comparable spatial resolution. The new approach has the potential of isolating the signals from each of the separate retinotopically organized visual areas. Information on the recent advances can be found at Localization in Time and Space of Evoked EEG and MEG Sources. For details on our earlier research see the Nonlinear Systems Analysis and Visual Evoked Potentials publications plus the associated "Research Commentaries".

An MRI with the white and gray matter segmented.

Developing a Model of Spatial Vision
The visual system consists of an enormous number of spatial filters with different positions, sizes, orientations and bandwidths. These filters are arranged in sequential stages with nonlinear interactions among and within the stages. In collaboration with Dennis Levi's group we do psychophysical experiments to characterize these stages of visual processing and their interactions. The role of top-down feedback is especially interesting because we intend to carry out parallel experiments with VEP/MEG/fMRI source localization. We also study the effects of visual noise and the effects of visual learning on human performance. One result of this research is that we now hold the Guinness record for position acuity. This modeling research has applications to image compression. For further details see the Spatial Vision and Applied Vision publications together with the associated "Research Commentaries".